Portfolio
Kcat Enzymatic
AI-enabled enzyme engineering for sustainable chemical manufacturing.
Sector
BioTech
Fund
Fund I
Invested at
Seed Stage
Status
Scaling from product validation to commercial deployment.
Chemistry run at lower temperature and pressure.
Kcat Enzymatic is a protein and enzyme engineering company developing optimised biocatalysts for industrial applications. The company applies scientific and computational approaches to discover, design and improve enzymes that can make chemical production faster, more selective and more resource-efficient.
Enzymes are biological catalysts that can enable manufacturing at lower temperatures and pressures, reduce waste and improve process precision. Kcat’s work is relevant across chemical, pharmaceutical, food, materials and other sectors requiring higher-yield and lower-impact production processes.
The company combines customised enzyme development with an application-led focus: creating biocatalysts suited to a customer’s specific substrate, process condition and performance requirement. Its platform can help industrial users improve conversion, selectivity, productivity and sustainability.
FoundersGladstone Sigamani and Pravin Kumar 
What they doKcat’s enzyme-engineering laboratory 
What they doThe Kcat team in the lab
Why we invested
Biocatalysis will reshape how molecules are made.
Enzymes let manufacturing run at lower temperatures and pressures, with less waste and more precision. Designing them to a customer's specific substrate and process condition is what makes that shift practical at industrial scale.
- SPECIALITY CHEMICALS
- PHARMACEUTICALS
- FOOD AND NUTRITION
- MATERIALS
- SUSTAINABLE MANUFACTURING
Kcat is building for that world.
Company snapshot
Category
Biotech / Industrial Biocatalysis
Founders
- Gladstone Sigamani Co-Founder & CEO
- Pravin Kumar Co-Founder & CSO
Technology highlights
- Enzyme discovery and protein engineering
- Customised biocatalysts for industrial processes
- Data- and AI-enabled enzyme optimisation
- Higher yield, selective chemistry and process efficiency
- Applications in sustainable chemical manufacturing
8X View
Hard environments create hard companies.
We back founders building technology where the barrier is not just software speed, but engineering depth, technical resilience and real-world deployment.
Kcat reflects that thesis.